Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 112, Issue -, Pages 521-524Publisher
ELSEVIER
DOI: 10.1016/j.colsurfb.2013.08.026
Keywords
MoO3; Nanoplates; Antibacterial activity; Membrane disruption; Minimum inhibitory concentration
Funding
- National Research Foundation of Korea [2011-0015829]
Ask authors/readers for more resources
Inorganic nanostructures are highly recognized for their potential use in the development of new functional materials for biomedical applications. In this study, we investigated the antibacterial efficiency of molybdenum trioxide (MoO3) nanoplates against four types of pathogenic bacteria. MoO3 nanoplates are synthesized by a simple wet chemical approach. X-ray diffraction and FT-IR analysis showed the presence of an orthorhombic phase of MoO3 nanoplates. Field emission scanning electron microscope studies confirmed the formation of plate-like structures of MoO3. The minimum inhibitory concentration (MIC) of MoO3 nanoplates against pathogenic bacteria was evaluated using a microdilution method. MICs such as 8 mu g/mL (against Escherichia coli and Salmonella typhimurium), 16 mu g/mL (against Enterococcus faecalis), and 8 mu g/mL (against Bacillus subtilis) show that MoO3 nanoplates have predominant antibacterial activity compared to the standard antibiotic, kanamycin. Evaluation of bacterial enzymatic (beta-D-galactosidase) activity in the hydrolysis of o-nitrophenol and beta-D-galactopyranoside suggested the disruption of the bacterial cell wall mechanism responsible for bacterial toxicity. (C) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available