Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 101, Issue -, Pages 97-100Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2012.06.001
Keywords
Hollow silica sphere; Silica-Ag; Antibacterial efficacy
Funding
- National Natural Science Foundation of China [301101388, 31000076]
- Natural Science Foundation of Jiangsu Province [BK2011468, BK2009720]
- Jiangsu provincial government study abroad scholarship
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- foundation of Jiangsu University [11JDG098]
- Villum Fonden [00007194] Funding Source: researchfish
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Hollow silica spheres with round mesoporous shells were synthesized by core-shell template method, using monodispersed cationic polystyrene particles as core, and TEOS (tetraethoxysilane) as the silica source to form shell. After calcination at 550 degrees C, uniform spheres with a thin shell of silica and hollow interior structures. Transmission electron microscopy results showed that the size of the spheres is about 700 nm in diameter with narrow distribution. In addition, the spheres have a high surface area of 183 m(2)/g. The spheres were subsequently used as silver-loading substrates and the silver loaded spheres were tested in antimicrobial study against gram negative bacteria Eschrichia coli in vitro. The hollow silica-Ag spheres proved significantly higher antibacterial efficacy against E. coli as compared to that of the common silica-Ag particles. (C) 2012 Elsevier B.V. All rights reserved.
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