Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 87, Issue 1, Pages 18-22Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2011.03.030
Keywords
Single walled carbon nanotubes; Chitosan; Biosensor; Disposable pencil graphite electrode; Vitamin B-12
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A single walled carbon nanotube-chitosan (SWCNT-chitosan) modified disposable pencil graphite electrode (PGE) was used in this study for the electrochemical detection of Vitamin B-12. Electrochemical behaviors of SWCNT-chitosan PGE and chitosan modified PGE were compared by using cyclic voltammetry (CV), square-wave voltammetry (SWV) and electrochemical impedance spectroscopy (EIS) techniques. SWCNT-chitosan modified electrode was also used for the quantification of Vitamin B-12 in pharmaceutical products. The results show that this electrode system is suitable for sensitive Vitamin B-12 analysis giving good recovery results. The surface morphologies of the SWCNT-chitosan PGE, chitosan modified PGE and unmodified PGE were characterized by using scanning electron microscopy (SEM). (C) 2011 Elsevier B.V. All rights reserved.
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