Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 88, Issue 2, Pages 729-733Publisher
ELSEVIER
DOI: 10.1016/j.colsurfb.2011.08.008
Keywords
Artesunate; Solubilized system; Pharmaceuticals formulation; Biological fluids
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The voltammetric behaviour of artesunate is studied at glassy carbon electrode in different buffer systems using square wave, differential pulse and cyclic voltammetric techniques. The peak current is linear with the drug concentration in the range 4.0-40 mu g mL(-1) for serum, plasma and urine. The mean percentage recoveries of the drug, urine, plasma and serum samples are 98.6-100.2%. No electroactive interferences from the excipients and endogenous substance could be observed in the pharmaceutical dosage forms and in biological samples. (C) 2011 Elsevier B.V. All rights reserved.
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