Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 73, Issue 2, Pages 376-381Publisher
ELSEVIER
DOI: 10.1016/j.colsurfb.2009.06.009
Keywords
Control release; Emulsion electrospinning; Nanofibers; PLLACL
Funding
- National Science Foundation [30570503]
- National High Technology Research and Developed Program [2008AA03Z305]
- Science and Technology Commission of Shanghai Municipality Program [08520704600, 0852nm03400]
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The purpose of this work is to develop a novel type of tissue engineering scaffold or drugs delivery carrier with the capability of encapsulation and controlled release drugs. In this study, Rhodamine B and Bovine Serum Albumin (BSA) were successfully incorporated into nanofibers by means of emulsion electrospinning. The morphology of composite nanofibers was studied by Scanning Electron Microscopy (SEM). The composite nanofibrous mats made from emulsion electrospinning were characterized by water contact angle measurement and X-ray diffraction. In vitro dual drugs release behaviors from composite nanofibrous mats were investigated. The results indicated that the incorporated drug and/or proteins in composite fibrous mats made from electrospinning could be control released by adjusting the processes of emulsions preparation. (c) 2009 Elsevier B.V. All rights reserved.
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