Journal
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
Volume 9, Issue 1, Pages 44-58Publisher
SPRINGER
DOI: 10.3758/CABN.9.1.44
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [30711120563, 30670704, 60605016, 60535030, 60435010]
- National High Technology Research and Development Program of China [2006AA01Z196, 2006AA010103]
- Trans-Century Training Program Foundation for the Talents by the State Education Commission
- Peking University
Ask authors/readers for more resources
Attention to a prepulse presented shortly before a startling stimulus enhances prepulse inhibition (PPI) of startle in normal people, but not in schizophrenics. Fear conditioning for the prepulse enhances PPI in socially reared, but not isolation-reared, rats. In humans, selective attention to acoustic signals against masking can be facilitated by precedence-effect-induced perceived spatial separation between the signal and the masker. This study investigated whether perceived spatial separation between a prepulse and a noise masker enhances PPI in socially reared rats and isolation-reared rats. The results show that both PPI and conditioning-induced PPI enhancement were larger in socially reared rats than in isolation-reared rats. More important, in socially reared, but not isolation-reared, rats, a further PPI enhancement was induced by precedence-effect-induced perceived separation between a prepulse and a masker only after the prepulse became fear conditioned. Thus, perceived separation facilitates normal rats' attention to a conditioned prepulse and enhances PPI. Isolation rearing impairs rats' ability to attend to ecologically significant acoustic events.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available