Journal
CNS SPECTRUMS
Volume 18, Issue -, Pages 22-33Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1092852913000734
Keywords
Antidepressant treatment; major depressive disorder; monoamine oxidase inhibition
Categories
Funding
- Mylan Specialty L.P.
Ask authors/readers for more resources
The goal of this brief review is to explain the role of monoamine oxidase enzymes in the neurobiology, etiology, and presentation of psychiatric illnesses, primarily major depressive disorder. This article will initially focus on the basic science and function of the monoamine oxidase system and some proposed neuropsychiatric symptoms that may arise if this enzyme system is altered by genetic predisposition. These findings and theories will next be translationally discussed in regard to clinical application pertaining to enzyme inhibition and the treatment of major depressive and other psychiatric disorders.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available