Journal
CNS SPECTRUMS
Volume 13, Issue 1, Pages 32-+Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1092852900016138
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Funding
- NIDA NIH HHS [R01 DA015207-02, R01 DA015207-03, R01 DA015207, DA15207] Funding Source: Medline
- NIMH NIH HHS [R03 MH070624-02, MH70624, R03 MH070624] Funding Source: Medline
- NINDS NIH HHS [R01 NS023805-19A2, NS23805, R01 NS023805-18, R01 NS023805] Funding Source: Medline
- NATIONAL INSTITUTE OF MENTAL HEALTH [R03MH070624] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS023805] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA015207] Funding Source: NIH RePORTER
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This review begins with a description of some problems that recently have beset an influential circuit model of fear conditioning and goes on to look at neuroanatomy that may subserve conditioning viewed in a broader perspective, including not only fear but also appetitive conditioning. The column will then focus on basal forebrain functional-anatomical systems, or macrosystems, as they have come to be called. Yet, more specific attention is then given to the relationships of the dorsal and ventral striatopallidal systems and extended amygdala with the dopaminergic mesotelencephalic projection systems, culminating with the hypothesis that all macrosystems contribute to behavioral conditioning.
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