Journal
CLINICS IN SPORTS MEDICINE
Volume 31, Issue 4, Pages 645-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.csm.2012.07.003
Keywords
Tendon biology; Bone morphogenetic protein; Growth factors; Repair scaffolds
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Surgical repair of rotator cuff tears is a relatively common orthopedic procedure. Although the procedure is clinically successful, the repair site frequently has incomplete healing and gap formation, owing to a fibrovascular scar-mediated healing response at the tendon-bone interface. By augmenting the repair site with biological agents, the ultimate goal is to stimulate a regenerative healing pathway. Challenges remain, however, regarding the ideal factor(s), timing, and vehicle of delivery.
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