Journal
CLINICS IN PLASTIC SURGERY
Volume 36, Issue 4, Pages 661-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cps.2009.05.014
Keywords
Burns; Hypertrophic scar; Treatment; Outcome; Fibroproliferative disorder
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Fibroproliferative disorders (FPDs) are common and serious disorders. Hypertrophic scar (HSc) and keloids represent the dermal equivalents of FPD and impose lower mortality but great morbidity. This article reviews current knowledge in the pathophysiology and molecular and cellular characteristics of postburn HSc. Additionally, current treatment modalities and future treatment options based on advancements in the understanding of the pathophysiology of HSc are discussed.
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