Journal
CLINICS IN GERIATRIC MEDICINE
Volume 26, Issue 3, Pages 355-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cger.2010.03.001
Keywords
Osteoarthritis; Weight-bearing joints; Risk factors
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Funding
- NIAMS NIH HHS [P60 AR047785, K23 AR055127] Funding Source: Medline
- NIAMS NIH HHS [P60 AR047785-029001, P60 AR047785] Funding Source: Medline
- NIEHS NIH HHS [P30 ES010126] Funding Source: Medline
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Osteoarthritis (OA) is the most common joint disorder in the United States. Symptomatic knee OA occurs in 10% men and 13% in women aged 60 years or older. The number of people affected with symptomatic OA is likely to increase due to the aging of the population and the obesity epidemic. OA has a multifactorial etiology, and can be considered the product of an interplay between systemic and local factors. Old age, female gender, overweight and obesity, knee injury, repetitive use of joints, bone density, muscle weakness, and joint laxity all play roles in the development of joint OA, particularly in the weight-bearing joints. Modifying these factors may reduce the risk of OA and prevent subsequent pain and disability.
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