Journal
CLINICS IN DERMATOLOGY
Volume 30, Issue 6, Pages 565-572Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.clindermatol.2012.01.002
Keywords
-
Categories
Ask authors/readers for more resources
Blastomycosis is a systemic mycosis with a high prevalence in the Midwest of the United States. The fungus inhabits soil, and human infection occurs through inhalation. Its asexual phase is called Blastomyces dermatitidis and its sexual phase, Ajellomyces dermatitidis. It is more common in men. Signs and symptoms are usually severe, starting with an infection resembling pneumonia that later disseminates to the skin, bones, and central nervous system. Infection in dogs is common in endemic areas. The diagnosis can be achieved by identifying the organism with direct microscopy, culture, histopathology, serologic tests, and molecular techniques, although these are still in trial phase. The treatments of choice are azoles (itraconazole, fluconazole, and posaconazole), and in severe cases, amphotericin B. (C) 2012 Published by Elsevier Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available