Journal
CLINICS IN DERMATOLOGY
Volume 27, Issue 2, Pages 202-209Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.clindermatol.2008.04.003
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For many years, melatonin has been known to interact with circadian rhythms. New evidence indicates that melatonin acts as a free radical scavenger and antioxidant. Moreover, melatonin prevents apoptosis in different types of cells, because it induces mRNA levels of several antioxidant enzymes. It is evident that melatonin is involved in the cellular bioenergetic system as a mechanism that counteracts the progression of Alzheimer's disease. (c) 2009 Elsevier Inc. All rights reserved.
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