Journal
CLINICS
Volume 64, Issue 4, Pages 357-362Publisher
HOSPITAL CLINICAS, UNIV SAO PAULO
DOI: 10.1590/S1807-59322009000400015
Keywords
Arthritis; Plant extract; Aspirin; Collagen; Rat
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OBJECTIVE: To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND METHOD: The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin. RESULTS: The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.
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