Journal
CLINICAL TRANSPLANTATION
Volume 24, Issue 2, Pages 149-156Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1399-0012.2010.01232.x
Keywords
dermatologic complications; immunosuppression; renal transplantation; sirolimus
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Funding
- MediMedia Educational Group, LLC
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Mammalian target of rapamycin inhibitor use is associated with numerous adverse events, including dermatologic and mucosal problems. Awareness of these complications, which clinically manifest across a severity spectrum from minor through severe and may occur at varied time points after initiation of sirolimus therapy, can be useful to clinicians in both managing these events and determining the appropriate intervention(s) for patients. This manuscript examines the dermatologic and mucosal problems associated with mammalian target of rapamycin inhibitor use, reviews the literature, and provides personal experiences regarding the management and treatment of these adverse events.
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