4.7 Review

Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

Related references

Note: Only part of the references are listed.
Article Endocrinology & Metabolism

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hye-Mi Lee et al.

DIABETES (2013)

Article Endocrinology & Metabolism

Glucagon regulates ACC activity in adipocytes through the CAMKKβ/AMPK pathway

I-Chen Peng et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)

Article Cardiac & Cardiovascular Systems

Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase

Kosaku Iwatsubo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)

Review Biochemistry & Molecular Biology

AMP-activated protein kinase: new regulation, new roles?

David Carling et al.

BIOCHEMICAL JOURNAL (2012)

Review Cell Biology

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

Christopher K. Glass et al.

CELL METABOLISM (2012)

Article Cardiac & Cardiovascular Systems

Brown Adipose Tissue Mechanisms and Potential Therapeutic Targets

Charmaine S. Tam et al.

CIRCULATION (2012)

Review Endocrinology & Metabolism

Adiponectin: mechanistic insights and clinical implications

A. T. Turer et al.

DIABETOLOGIA (2012)

Review Pharmacology & Pharmacy

Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

Ian P. Salt et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)

Article Endocrinology & Metabolism

Regulation of LKB1 expression by sex hormones in adipocytes

K. J. McInnes et al.

INTERNATIONAL JOURNAL OF OBESITY (2012)

Review Cell Biology

The role of the mineralocorticoid receptor in adipocyte biology and fat metabolism

Vincenzo Marzolla et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)

Review Biotechnology & Applied Microbiology

Leptin revisited: its mechanism of action and potential for treating diabetes

Roberto Coppari et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Review Cell Biology

AMPK: a nutrient and energy sensor that maintains energy homeostasis

D. Grahame Hardie et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Multidisciplinary Sciences

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Simon A. Hawley et al.

SCIENCE (2012)

Article Pharmacology & Pharmacy

Activation of AMP-Activated Protein Kinase Inhibits the Proliferation of Human Endothelial Cells

Kelly J. Peyton et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)

Article Endocrinology & Metabolism

Homocysteine suppresses lipolysis in adipocytes by activating the AMPK pathway

Zhigang Wang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Article Physiology

Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in α1-AMPK-/- mice

Jake D. Bauwens et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)

Article Physiology

Glucose homeostasis in rainbow trout fed a high-carbohydrate diet: metformin and insulin interact in a tissue-dependent manner

S. Polakof et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype

Karin Kohlstedt et al.

BASIC RESEARCH IN CARDIOLOGY (2011)

Article Biochemistry & Molecular Biology

Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα

Milica Vucetic et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2011)

Review Biochemistry & Molecular Biology

Several agents and pathways regulate lipolysis in adipocytes

Valeria Ernestania Chaves et al.

BIOCHIMIE (2011)

Article Cell Biology

Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype

Maryam Ahmadian et al.

CELL METABOLISM (2011)

Article Biochemistry & Molecular Biology

Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissue in Vivo

Thomas Pulinilkunnil et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

Obestatin as a regulator of adipocyte metabolism and adipogenesis

Uxia Gurriaran-Rodriguez et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)

Article Medicine, Research & Experimental

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

Sandra Galic et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Biochemistry & Molecular Biology

SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

Partha Chakrabarti et al.

JOURNAL OF LIPID RESEARCH (2011)

Article Biochemistry & Molecular Biology

Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity

Mandeep P. Gaidhu et al.

JOURNAL OF LIPID RESEARCH (2011)

Article Biochemistry & Molecular Biology

Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK), RSVA314 and RSVA405, Inhibit Adipogenesis

Valerie Vingtdeux et al.

MOLECULAR MEDICINE (2011)

Article Biochemistry & Molecular Biology

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Bolormaa Vandanmagsar et al.

NATURE MEDICINE (2011)

Article Endocrinology & Metabolism

Metformin induces glucose uptake in human preadipocyte-derived adipocytes from various fat depots

M. Fischer et al.

DIABETES OBESITY & METABOLISM (2010)

Review Peripheral Vascular Disease

Adipose Tissue, Inflammation and Atherosclerosis

Birgit Gustafson

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2010)

Article Biochemistry & Molecular Biology

Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes

Daniel J. Fazakerley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

AMPK beta 1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance

Nicolas Dzamko et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

Zhenggang Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity

Gregory R. Steinberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase

Jaroslaw W. Zmijewski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells

Robin E. Duncan et al.

JOURNAL OF LIPID RESEARCH (2010)

Article Endocrinology & Metabolism

Differences in AMPK expression between subcutaneous and visceral adipose tissue in morbid obesity

O. Martinez-Agustin et al.

REGULATORY PEPTIDES (2010)

Article Endocrinology & Metabolism

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

Hyun Woo Jeong et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Article Endocrinology & Metabolism

Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes

Christine Berggreen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Article Pharmacology & Pharmacy

Inhibitory Effects of A-769662, a Novel Activator of AMP-Activated Protein Kinase, on 3T3-L1 Adipogenesis

Yi Zhou et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)

Review Cell Biology

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

Bei B. Zhang et al.

CELL METABOLISM (2009)

Article Medicine, Research & Experimental

Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes

Silvia Lorente-Cebrian et al.

CLINICAL SCIENCE (2009)

Article Endocrinology & Metabolism

Mechanisms of metformin inhibiting lipolytic response to isoproterenol in primary rat adipocytes

Tingting Zhang et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2009)

Review Endocrinology & Metabolism

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

Kei Sakamoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

Shuai Chen et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

AMPK and PPARδ Agonists are exercise mimetics

Vihang A. Narkar et al.

Article Biochemistry & Molecular Biology

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

John W. Scott et al.

CHEMISTRY & BIOLOGY (2008)

Review Endocrinology & Metabolism

Minireview: Lipid droplets in lipogenesis and lipolysis

Nicole A. Ducharme et al.

ENDOCRINOLOGY (2008)

Article Biochemistry & Molecular Biology

AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte - Potential mechanism and physiological relevance

Marie-Soleil Gauthier et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Endocrinology & Metabolism

Changes in Adenosine 5′-Monophosphate-Activated Protein Kinase as a Mechanism of Visceral Obesity in Cushing's Syndrome

Blerina Kola et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)

Article Cell Biology

The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells

Aina S. Lihn et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)

Article Biochemistry & Molecular Biology

The selectivity of protein kinase inhibitors: a further update

Jenny Bain et al.

BIOCHEMICAL JOURNAL (2007)

Article Biochemistry & Molecular Biology

Compound C inhibits hypoxic activation of HIF-1 independent of AMPK

Brooke M. Emerling et al.

FEBS LETTERS (2007)

Article Biochemistry & Molecular Biology

Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR

Kathryn M. Geraghty et al.

BIOCHEMICAL JOURNAL (2007)

Article Multidisciplinary Sciences

Structural basis for AMP binding to mammalian AMP-activated protein kinase

Bing Xiao et al.

NATURE (2007)

Article Multidisciplinary Sciences

Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

Justin I. Odegaard et al.

NATURE (2007)

Article Medicine, Research & Experimental

Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

Andrea L. Hevener et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes

Bai Luo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Endocrinology & Metabolism

Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation

Laura Barre et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)

Article Cardiac & Cardiovascular Systems

Statins activate AMP-activated protein kinase in vitro and in vivo

Wei Sun et al.

CIRCULATION (2006)

Article Medicine, Research & Experimental

TLR4 links innate immunity and fatty acid-induced insulin resistance

Hang Shi et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Cell Biology

Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation

Divya Vats et al.

CELL METABOLISM (2006)

Review Neurosciences

Functions of AMP-activated protein kinase in adipose tissue

Marie Daval et al.

JOURNAL OF PHYSIOLOGY-LONDON (2006)

Article Medicine, Research & Experimental

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Hajime Kanda et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Endocrinology & Metabolism

Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue

MJ Watt et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Endocrinology & Metabolism

Adiponectin receptors in human adipose tissue: Effects of obesity, weight loss, and fat depots

Maria S. Rasmussen et al.

OBESITY (2006)

Article Multidisciplinary Sciences

Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity

MY Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Involvement of AMP-activated protein kinase in fat depot-specific metabolic changes during starvation

J Sponarova et al.

FEBS LETTERS (2005)

Article Biochemistry & Molecular Biology

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

S Cinti et al.

JOURNAL OF LIPID RESEARCH (2005)

Article Biochemistry & Molecular Biology

Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes

M Daval et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

AICAR stimulates adiponectin and inhibits cytokines in adipose tissue

A Lihn et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Multidisciplinary Sciences

Rapid transformation of white adipocytes into fat-oxidizing machines

L Orci et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Endocrinology & Metabolism

Activity of LKB1 and AMPK-related kinases in skeletal muscle:: Effects of contraction, phenformin, and AICAR

K Sakamoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Biochemistry & Molecular Biology

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise

M Kelly et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Multidisciplinary Sciences

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

R Zimmermann et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes

CL Su et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis in 3T3-L1 adipocytes

W Yin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

Glyceroneogenesis and the triglyceride/fatty acid cycle

L Reshef et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

H Sano et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways

LGD Fryer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Endocrinology & Metabolism

Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes

H Sakoda et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)

Article Endocrinology & Metabolism

Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation

JS Fisher et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)

Article Endocrinology & Metabolism

Regulation of GLUT4 biogenesis in muscle:: evidence for involvement of AMPK and Ca2+

EO Ojuka et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)

Article Multidisciplinary Sciences

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Y Minokoshi et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

The effects of AICAR on adipocyte differentiation of 3T3-L1 cells

SA Habinowski et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Article Biochemistry & Molecular Biology

Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin

N Perrotti et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Characterization of AMP-activated protein kinase γ-subunit isoforms and their role in AMP binding

PCF Cheung et al.

BIOCHEMICAL JOURNAL (2000)