Related references
Note: Only part of the references are listed.Morphologic Findings in Progressive Familial Intrahepatic Cholestasis 2 (PFIC2): Correlation With Genetic and Immunohistochemical Studies
Kimberley Evason et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2011)
Endoplasmic reticulum stress in liver disease
Harmeet Malhi et al.
JOURNAL OF HEPATOLOGY (2011)
NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells
E. Crescenzi et al.
ONCOGENE (2011)
Longitudinal Profiles of 15 Serum Bile Acids in Patients With Intrahepatic Cholestasis of Pregnancy
Rachel M. Tribe et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2010)
Enhanced Hepatic Nrf2 Activation After Ursodeoxycholic Acid Treatment in Patients with Primary Biliary Cirrhosis
Kazuhito Kawata et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Cystic fibrosis-associated liver disease
Ulrike Herrmann et al.
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2010)
Ursodeoxycholic acid modulates the ubiquitin-proteasome degradation pathway of p53
Joana D. Amaral et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Tauroursodeoxycholate counteracts hepatocellular lysis induced by tensioactive bile salts by preventing plasma membrane-micelle transition
Cecilia L. Basiglio et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Bile salts and cholestasis
Lucas Maillette de Buy Wenniger et al.
DIGESTIVE AND LIVER DISEASE (2010)
Ursodeoxycholic acid and chemoprevention of colorectal cancer
L. Serfaty et al.
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE (2010)
Pathogenesis of Cholestatic Liver Disease and Therapeutic Approaches
Gideon M. Hirschfield et al.
GASTROENTEROLOGY (2010)
Biliary Secretion of S-Nitrosoglutathione Is Involved in the Hypercholeresis Induced by Ursodeoxycholic Acid in the Normal Rat
Carlos M. Rodriguez-Ortigosa et al.
HEPATOLOGY (2010)
Bile Acid Changes After High-Dose Ursodeoxycholic Acid Treatment in Primary Sclerosing Cholangitis: Relation to Disease Progression
Emmanouil Sinakos et al.
HEPATOLOGY (2010)
High-Dose Ursodeoxycholic Acid Therapy for Nonalcoholic Steatohepatitis: A Double-Blind, Randomized, Placebo-Controlled Trial
Ulrich F. H. Leuschner et al.
HEPATOLOGY (2010)
Biliary Apotopes and Anti-Mitochondrial Antibodies Activate Innate Immune Responses in Primary Biliary Cirrhosis
Ana Lleo et al.
HEPATOLOGY (2010)
A pilot trial of high-dose ursodeoxycholic acid in nonalcoholic steatohepatitis
Leon A. Adams et al.
HEPATOLOGY INTERNATIONAL (2010)
Liver disease associated with canalicular transport defects: Current and future therapies
Janneke M. Stapelbroek et al.
JOURNAL OF HEPATOLOGY (2010)
Anti-oxidants do not prevent bile acid-induced cell death in rat hepatocytes
Titia E. Woudenberg-Vrenken et al.
LIVER INTERNATIONAL (2010)
Nuclear Receptor Regulation of the Adaptive Response of Bile Acid Transporters in Cholestasis
Martin Wagner et al.
SEMINARS IN LIVER DISEASE (2010)
The Spectrum of Liver Diseases Related to ABCB4 Gene Mutations: Pathophysiology and Clinical Aspects
Anne Davit-Spraul et al.
SEMINARS IN LIVER DISEASE (2010)
Kinetic analysis of bile acid sulfation by stably expressed human sulfotransferase 2A1 (SULT2A1)
J. Huang et al.
XENOBIOTICA (2010)
Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells
Sakiko Arisawa et al.
BIOCHEMICAL PHARMACOLOGY (2009)
The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid
Yong Zhou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Differential effects of silymarin and its active component silibinin on plasma membrane stability and hepatocellular lysis
Cecilia L. Basiglio et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Apoptosis and Cytokinesin Non-Alcoholic Steatohepatitis
Wing-Kin Syn et al.
CLINICS IN LIVER DISEASE (2009)
Endoplasmic Reticulum Stress and the Unfolded Protein Response
Ashwani Kapoor et al.
CLINICS IN LIVER DISEASE (2009)
Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers
Andreas E. Kremer et al.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2009)
Activation of the Cholehepatic Shunt as a Potential Therapy for Primary Sclerosing Cholangitis
Shannon S. Glaser et al.
HEPATOLOGY (2009)
High-Dose Ursodeoxycholic Acid for the Treatment of Primary Sclerosing Cholangitis
Keith D. Lindor et al.
HEPATOLOGY (2009)
Control of mitochondrial apoptosis by the Bcl-2 family
Joslyn K. Brunelle et al.
JOURNAL OF CELL SCIENCE (2009)
Effects of ursodeoxycholic acid in combination with vitamin E on adipokines and apoptosis in patients with nonalcoholic steatohepatitis
Maria Luisa Balmer et al.
LIVER INTERNATIONAL (2009)
Bile-acid-induced cell injury and protection
Maria J. Perez et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
Kosuke Okada et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1
Thomas Pusl et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Ursodeoxycholic acid protects concanavalin A-induced mouse liver injury through inhibition of intrahepatic tumor necrosis factor-α and macrophage inflammatory protein-2 production
Kaoru Ishizaki et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKCα-/PKA-dependent mechanism in rat liver
R. Wimmer et al.
GUT (2008)
Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver
Gerald Ulrich Denk et al.
HEPATOLOGY RESEARCH (2008)
Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases
Hideyuki Kojima et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2008)
Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease
Kazuyoshi Takeda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease
Rita M. Ramalho et al.
TRENDS IN MOLECULAR MEDICINE (2008)
Nuclear hormone receptor-dependent regulation of hepatic transporters and their role in the adaptive response in cholestasis
S. Stahl et al.
XENOBIOTICA (2008)
Role of ursodeoxycholic acid in prevention of methotrexate-induced liver toxicity
Suleyman Uraz et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
Ursodeoxycholic acid in chronic hepatitis C
Raoul Poupon et al.
GUT (2007)
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
Jyoti D. Malhotra et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis
Joana D. Amaral et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion
Romina Fiorotto et al.
GASTROENTEROLOGY (2007)
Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin
Adelaide Fernandes et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Clinical and pathological features of a prolonged type of acute intrahepatic cholestasis
Norihito Watanabe et al.
HEPATOLOGY RESEARCH (2007)
Tauroursodeoxycholic acid inhibits apoptosis induced by Z alpha-1 antitrypsin via inhibition of Bad
Stanley D. W. Miller et al.
HEPATOLOGY (2007)
Low phospholipid associated cholelithiasis:: association with mutation in the MDR3/ABCB4 gene
Olivier Rosmorduc et al.
ORPHANET JOURNAL OF RARE DISEASES (2007)
Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell lines
Hui Liu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2007)
Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem cell transplantation
Jason Tay et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2007)
Bile acids for viral hepatitis
W. Chen et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2007)
Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration
Andreas Geier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Endoplasmic reticulum stress and apoptosis
Jitka Faitova et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2006)
Involvement of endoplasmic reticulum in glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes
Shizuma Tsuchiya et al.
TOXICOLOGY LETTERS (2006)
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
Umut Oezcan et al.
SCIENCE (2006)
Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy
Verena Keitel et al.
GASTROENTEROLOGY (2006)
Coordinated induction of bile acid detoxification and alternative elimination in mice:: role of FXR-regulated organic solute transporter-α/β in the adaptive response to bile acids
G Zollner et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Ursodeoxycholic acid inhibits interleukin beta 1 and deoxycholic acid-induced activation of NF-κB and AP-1 in human colon cancer cells
SA Shah et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis
C Bernt et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice
P Fickert et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
P Fickert et al.
GASTROENTEROLOGY (2006)
Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver
F Dombrowski et al.
LABORATORY INVESTIGATION (2006)
Bile salt-induced apoptosis involves NADPH oxidase isoform activation
R Reinehr et al.
GASTROENTEROLOGY (2005)
Novel biotransformation and physiological properties of norursodeoxycholic acid in humans
AF Hofmann et al.
HEPATOLOGY (2005)
The effect of ursodeoxycholic acid on glycochenodeoxycholic acid-induced apoptosis in rat hepatoctes
S Utanohara et al.
TOXICOLOGY (2005)
Vanishing bile duct syndrome:: Amoxicillin-clavulanic acid associated intra-hepatic cholestasis responsive to ursodeoxycholic acid
LA Smith et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2005)
Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-β1-induced apoptosis in rat hepatocytes
S Solá et al.
HEPATOLOGY (2005)
Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids
TJ Sokol et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2005)
Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat
FA Crocenzi et al.
DRUG METABOLISM AND DISPOSITION (2005)
Oncosis represents the main type of cell death in mouse models of cholestasis
P Fickert et al.
JOURNAL OF HEPATOLOGY (2005)
No relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis
K Dilger et al.
HEPATOLOGY (2005)
Modulation of apoptosis as a target for liver disease
ST Eichhorst
EXPERT OPINION ON THERAPEUTIC TARGETS (2005)
The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis
C Corpechot et al.
GASTROENTEROLOGY (2005)
Signaling modulation of bile salt-induced necrosis in isolated rat hepatocytes
M Borgognone et al.
TOXICOLOGICAL SCIENCES (2005)
Ursodeoxycholic acid protects against secondary billary cirrhosis in rats by preventing mitochondrial oxidative stress
G Serviddio et al.
HEPATOLOGY (2004)
The protective effect of ursodeoxycholic acid in alloxan-induced diabetes
O Lukivskaya et al.
CELL BIOCHEMISTRY AND FUNCTION (2004)
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase
R Kubitz et al.
GASTROENTEROLOGY (2004)
Potential role of ursodeoxycholic acid in suppression of nuclear factor kappa B in microglial cell line (BV-2)
SS Joo et al.
ARCHIVES OF PHARMACAL RESEARCH (2004)
Ursodeoxycholic acid (UDCA) therapy in very-low-birth-weight infants with parenteral nutrition-associated cholestasis
CY Chen et al.
JOURNAL OF PEDIATRICS (2004)
Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways
MH Schoemaker et al.
HEPATOLOGY (2004)
Ursodeoxycholic acid for terbinafine-induced toxic hepatitis
E Agca et al.
ANNALS OF PHARMACOTHERAPY (2004)
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: The switch between apoptosis and necrosis
AP Rolo et al.
TOXICOLOGICAL SCIENCES (2004)
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine
G Zollner et al.
JOURNAL OF HEPATOLOGY (2003)
Biliary secretion of glutathione in estradiol 17β-D-glucuronide-induced cholestasis
AD Mottino et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice
M Wagner et al.
GASTROENTEROLOGY (2003)
Tauroursodeoxycholic acid prevents amyloid-β peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway
S Solá et al.
MOLECULAR MEDICINE (2003)
Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation
MH Schoemaker et al.
JOURNAL OF HEPATOLOGY (2003)
Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat
FA Crocenzi et al.
GUT (2003)
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis
G Zollner et al.
JOURNAL OF HEPATOLOGY (2003)
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats
CMP Rodrigues et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis
D Häussinger et al.
GASTROENTEROLOGY (2003)
Ursodeoxycholic acid therapy attenuated expression of adhesion molecule in primary biliary cirrhosis
H Yokomori et al.
INTERNAL MEDICINE (2003)
Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis
H Kojima et al.
JOURNAL OF HEPATOLOGY (2003)
Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein
RX Wang et al.
HEPATOLOGY (2003)
Antioxidant properties of ursodeoxycholic acid
D Lapenna et al.
BIOCHEMICAL PHARMACOLOGY (2002)
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy
JJ Lemasters et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles
P Fickert et al.
GASTROENTEROLOGY (2002)
Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation
Q Yie et al.
HEPATOLOGY (2002)
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic model of Huntington's disease
CD Keene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Effect of ursodeoxycholic acid on the expression of the hepatocellular bile acid transporters (Ntcp and bsep) in rats with estrogen-induced cholestasis
D Micheline et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2002)
Relief of extrinsic pathway inhibition by the bid-dependent mitochondrial release of smac in fas-mediated hepatocyte apoptosis
SC Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes
F Azzaroli et al.
HEPATOLOGY (2002)
Apoptosis of biliary epithelial cells in primary biliary cirrhosis and primary sclerosing cholangitis
J Tinmouth et al.
LIVER (2002)
An electron microscopic and morphometric study of ursodeoxycholic effect in primary biliary cirrhosis
MG Neuman et al.
LIVER (2002)
Altered localization and activity of canalicular Mrp2 in estradiol-17β-D-glucuronide-induced cholestasis
AD Mottino et al.
HEPATOLOGY (2002)
AP-1 as a regulator of cell life and death
E Shaulian et al.
NATURE CELL BIOLOGY (2002)
Activation of the metallothionein IIA promoter and other key stress response elements by ursodeoxycholate in HepG2 cells: Relevance to the cytoprotective function of ursodeoxycholate
C Bernstein et al.
PHARMACOLOGY (2002)
Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha
G Alpini et al.
HEPATOLOGY (2002)
Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
L Qiao et al.
HEPATOLOGY (2002)
Tumor necrosis factor-α and transforming growth factor-β reflect severity of liver damage in primary biliary cirrhosis
M Neuman et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2002)
Functional modulation of the glucocorticoid receptor and suppression of NF-κB-dependent transcription by ursodeoxycholic acid
T Miura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione
A Colell et al.
HEPATOLOGY (2001)
The bile acid glycochenodeoxycholate induces TRAIL-receptor 2/DR5 expression and apoptosis
H Higuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome p450
EG Schuetz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Stimulation of ATP secretion in the liver by therapeutic bile acids
MH Nathanson et al.
BIOCHEMICAL JOURNAL (2001)
Tauroursodesoxycholate-induced choleresis involves p38MAPK activation and translocation of the bile salt export pump in rats
AK Kurz et al.
GASTROENTEROLOGY (2001)
Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'
KN Lazaridis et al.
JOURNAL OF HEPATOLOGY (2001)
Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver
P Fickert et al.
GASTROENTEROLOGY (2001)
Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver
U Beuers et al.
HEPATOLOGY (2001)
Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
RJ Sokol et al.
PEDIATRIC RESEARCH (2001)
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
B Yerushalmi et al.
HEPATOLOGY (2001)
Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria
AP Rolo et al.
BIOSCIENCE REPORTS (2001)
Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: Evidence for a mitochondrial pathway independent of the permeability transition
CMP Rodrigues et al.
JOURNAL OF NEUROCHEMISTRY (2000)
The effect of ursodeoxycholic acid therapy on liver fibrosis progression in primary biliary cirrhosis
C Corpechot et al.
HEPATOLOGY (2000)
Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver
AK Kurz et al.
BIOCHEMICAL JOURNAL (2000)
Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver
CC Paulusma et al.
HEPATOLOGY (2000)
Expression of the bile salt export pump is maintained after chronic cholestasis in the rat
JM Lee et al.
GASTROENTEROLOGY (2000)
Share Paper
