Journal
CLINICAL RHEUMATOLOGY
Volume 29, Issue 1, Pages 111-113Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s10067-009-1269-x
Keywords
Hypertrophic pachymeningitis (HP); Myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA); Wegener's granulomatosis (WG)
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A 75-year-old man presented with headache, right facial palsy, and left hemiparesis. Because of elevated myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) titers and findings from magnetic resonance imaging (MRI) which were compatible with hypertrophic pachymeningitis (HP), he was diagnosed with MPO-ANCA-positive HP. He was treated with the combination therapy of steroid and cyclophosphamide (CY), leading to good prognosis. We present a case of HP associated with MPO-ANCA-positive vasculitis and emphasize the importance of MPO-ANCA tests as a predictable factor for relapse of the disease in order to start earlier treatment for the disease.
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