Journal
CLINICAL RHEUMATOLOGY
Volume 28, Issue 10, Pages 1235-1237Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s10067-009-1222-z
Keywords
Periodic fever; PFAPA in siblings; PFAPA syndrome
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PFAPA syndrome is characterized by episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. PFAPA syndrome usually begins in children under 5 years old and normally has self-resolution. The etiology of PFAPA syndrome remains unknown. In this paper, we report the cases of two different families with siblings with PFAPA syndrome: two sisters and two brothers. To our knowledge, this is the first report of siblings with PFAPA syndrome.
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