Journal
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
Volume 32, Issue 2, Pages 94-98Publisher
WILEY
DOI: 10.1111/j.1475-097X.2011.01060.x
Keywords
endothelium-independent dilation; gender; microcirculation; nitroglycerin; vascular function
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Funding
- NIDDK NIH HHS [R01 DK072124] Funding Source: Medline
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Background: A change in peripheral arterial tonometry (PAT) in response to reactive hyperaemia is often used to provide a non-invasive measure of endothelium-dependent dilation (EDD). Reactive hyperaemia does not allow one to quantify endothelium-independent dilation (EID), which is part of overall vascular function. Although most research examining vascular function and cardiovascular disease has focused on EDD, there is evidence that cardiovascular risk factors may impair EID.
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