Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 95, Issue 3, Pages 231-235Publisher
WILEY
DOI: 10.1038/clpt.2013.235
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Funding
- Canadian Institutes of Health Research [MOP86471, TMH 109787] Funding Source: Medline
- NIDA NIH HHS [DA020830] Funding Source: Medline
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Genetic information is increasingly used to optimize clinical treatment of patients, but obstacles remain to practical implementation as well as challenges to our understanding of genetic variation in drug response. These areas that particularly require research attention include gene-environment interactions, the consequences of genetic variation, and the impact of epigenetics on gene expression and function. In this issue of Clinical Pharmacology & Therapeutics focused on pharmacogenetics, we discuss some of the recent advances in understanding from a variety of viewpoints.
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