Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 93, Issue 4, Pages 324-325Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/clpt.2013.4
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Funding
- NCI NIH HHS [R25 CA023944, R37 CA036401] Funding Source: Medline
- NHLBI NIH HHS [U01 HL105198] Funding Source: Medline
- NIGMS NIH HHS [U01 GM092666] Funding Source: Medline
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The Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Thiopurine Methyltransferase Genotype and Thiopurine Dosing was originally published in March 2011. We reviewed recent literature and concluded that although relevant new evidence has been generated, none of the evidence would change the primary dosing recommendations in the original guideline; therefore, the original publication remains clinically current. Up-to-date information on thiopurine methyltransferase (TPMT) gene alleles and nomenclature can be found at PharmGKB (http://www.pharmgkb.org).
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