Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 90, Issue 1, Pages 164-168Publisher
WILEY
DOI: 10.1038/clpt.2011.105
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Funding
- National Institute on Drug Abuse [DA02277, U01 DA020830]
- National Cancer Institute [P50 CA143187]
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Smokers generally gain weight when they quit smoking; this weight gain can lessen some of the health benefits of quitting smoking. We review the effectiveness of behavioral and pharmacological approaches to mitigating weight gain in the context of quitting smoking and consider mechanisms that could potentially account for the effects of smoking and nicotine on body weight. Understanding how nicotine affects body weight may lead to novel pharmacological and behavioral interventions for obesity as well as concurrent obesity and nicotine dependence.
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