Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 83, Issue 4, Pages 615-618Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/clpt.2008.5
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Funding
- NCRR NIH HHS [UL1RR024143, UL1 RR024143] Funding Source: Medline
- NIDA NIH HHS [P60 DA005130, K05-DA00049, P60-DA-05130, K05 DA000049] Funding Source: Medline
- NIMH NIH HHS [R01 MH079880, 5R01-MH079880-02] Funding Source: Medline
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Over the past decade, enormous progress has been made in both the technical approaches and the scientific information available for studying the human genome. Therefore, increasingly, scientists have begun to address not just single-gene disorders but complex disorders. The limiting factor in most of such studies remains appropriate, well-focused detailed phenotyping of the complex disorders under study, with careful ascertainment of subjects with the specific disorder, as well as healthy control subjects.
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