Related references
Note: Only part of the references are listed.Surge in Expression of Carboxylesterase 1 During the Post-neonatal Stage Enables a Rapid Gain of the Capacity to Activate the Anti-influenza Prodrug Oseltamivir
Deshi Shi et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Practical lessons from the first outbreaks: Clinical presentation, obstacles, and management strategies for severe pandemic (pH1N1) 2009 influenza pneumonitis
Duane J. Funk et al.
CRITICAL CARE MEDICINE (2010)
Pharmacokinetics of oseltamivir: an oral antiviral for the treatment and prophylaxis of influenza in diverse populations
Brian E. Davies
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Oseltamivir Dosing for Influenza Infection in Premature Neonates
Edward P. Acosta et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin
Dongfang Yang et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Proposals for model-based paediatric medicinal development within the current European Union regulatory framework
Efthymios Manolis et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2009)
Limited Brain Distribution of [3R,4R,5S]-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate Phosphate (Ro 64-0802), a Pharmacologically Active Form of Oseltamivir, by Active Efflux across the Blood-Brain Barrier Mediated by Organic Anion Transporter 3 (Oat3/Slc22a8) and Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4)
Atsushi Ose et al.
DRUG METABOLISM AND DISPOSITION (2009)
Can we get the necessary clinical trials in children and avoid the unnecessary ones?
Kalle Hoppu
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2009)
The problems in scaling adult drug doses to children
T. N. Johnson
ARCHIVES OF DISEASE IN CHILDHOOD (2008)
Population pharmacokinetics of oseltamivir when coadministered with probenecid
Craig R. Rayner et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Applications of physiologically based absorption models in drug discovery and development
Neil Parrott et al.
MOLECULAR PHARMACEUTICS (2008)
Mechanistic approaches to volume of distribution predictions: Understanding the processes
Trudy Rodgers et al.
PHARMACEUTICAL RESEARCH (2007)
A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes of soman in multiple species
Richard E. Sweeney et al.
ARCHIVES OF TOXICOLOGY (2006)
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition
K. Bleasby et al.
XENOBIOTICA (2006)
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Trudy Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children
Trevor N. Johnson et al.
CLINICAL PHARMACOKINETICS (2006)
A novel strategy for physiologically based predictions of human pharmacokinetics
HM Jones et al.
CLINICAL PHARMACOKINETICS (2006)
Development and evaluation of a generic physiologically based pharmacokinetic model for children
Andrea N. Edginton et al.
CLINICAL PHARMACOKINETICS (2006)
Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling:: theophylline and midazolam as model drugs
S Björkman
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Tissue distribution of basic drugs:: Accounting for enantiomeric, compound and regional differences amongst β-blocking drugs in rat
T Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: Implications for assessing children's risks from environmental agents
G Ginsberg et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2004)
Developmental pharmacology - Drug disposition, action, and therapy in infants and children
GL Kearns et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation
PR Gentry et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2003)
The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion - Correlation of in vivo and in vitro studies
G Hill et al.
DRUG METABOLISM AND DISPOSITION (2002)
Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans
S Haddad et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A (2001)
Predicting the impact of physiological and biochemical processes on oral drug bioavailability
B Agoram et al.
ADVANCED DRUG DELIVERY REVIEWS (2001)
Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds
M Pelekis et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2001)
Share Paper
