Related references
Note: Only part of the references are listed.The Simcyp® Population-based ADME Simulator
Masoud Jamei et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2009)
Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches
Natilie A. Hosea et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2009)
Evaluation of a generic physiologically based pharmacokinetic model for lineshape analysis
Sheila Annie Peters
CLINICAL PHARMACOKINETICS (2008)
Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytes
Stuart W. Paine et al.
DRUG METABOLISM AND DISPOSITION (2008)
Whole body physiologically-based pharmacokinetic models: their use in clinical drug development
Andrea N. Edginton et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)
Challenges and opportunities with modelling and simulation in drug discovery and drug development
T. Lave et al.
XENOBIOTICA (2007)
Prediction of human pharmacokinetics using physiologically based modeling: A retrospective analysis of 26 clinically tested drugs
Stefan S. De Buck et al.
DRUG METABOLISM AND DISPOSITION (2007)
Evaluation of a basic physiologically based pharmacokinetic model for simulating the first-time-in-animal study
Massimiliano Germani et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2007)
Mechanistic approaches to volume of distribution predictions: Understanding the processes
Trudy Rodgers et al.
PHARMACEUTICAL RESEARCH (2007)
The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools
Stefan S. De Buck et al.
DRUG METABOLISM AND DISPOSITION (2007)
Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance
Hayley S. Brown et al.
DRUG METABOLISM AND DISPOSITION (2007)
Integrating in vitro ADMET data through generic physiologically based pharmacokinetic models
David E. Leahy
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Trudy Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Predicting pharmacokinetic food effects using biorelevant solubility media and physiologically based modelling
Hannah M. Jones et al.
CLINICAL PHARMACOKINETICS (2006)
A novel strategy for physiologically based predictions of human pharmacokinetics
HM Jones et al.
CLINICAL PHARMACOKINETICS (2006)
Prediction of in vivo drug clearance from in vitro data. I: Impact of inter-individual variability
E. M. Howgate et al.
XENOBIOTICA (2006)
An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery
N Parrott et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Physiologically based pharmacokinetic modeling 1: Predicting the tissue distribution of moderate-to-strong bases
T Rodgers et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Prediction of human drug clearance from in vitro and preclinical data using physiologically based and empirical approaches
K Ito et al.
PHARMACEUTICAL RESEARCH (2005)
A physiological model for the estimation of the fraction dose absorbed in humans
S Willmann et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Volume of distribution at steady state for a linear pharmacokinetic system with peripheral elimination
LM Berezhkovskiy
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance
DF McGinnity et al.
DRUG METABOLISM AND DISPOSITION (2004)
Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection
FP Theil et al.
TOXICOLOGY LETTERS (2003)
Whole body pharmacokinetic models
I Nestorov
CLINICAL PHARMACOKINETICS (2003)
Prediction of pharmacokinetics prior to in vivo studies.: II.: Generic physiologically based pharmacokinetic models of drug disposition
P Poulin et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution
P Poulin et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
Predicting the impact of physiological and biochemical processes on oral drug bioavailability
B Agoram et al.
ADVANCED DRUG DELIVERY REVIEWS (2001)
Share Paper
