4.5 Article

Shell technique using a rigid resorbable barrier system for localized alveolar ridge augmentation

Journal

CLINICAL ORAL IMPLANTS RESEARCH
Volume 25, Issue 2, Pages E149-E154

Publisher

WILEY
DOI: 10.1111/clr.12078

Keywords

alveolar ridge defect; animal study; barrier membranes; bone substitutes; guided bone regeneration

Funding

  1. KLS Martin, Muhlheim, Germany

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ObjectivesTo assess the safety and efficacy of a rigid synthetic barrier system in a shell technique for localized alveolar ridge augmentation. Materials and methodsSaddle-type defects (n=4 each) were prepared in the lower jaws of six fox hounds. At two defects, the outer contours were reconstructed using polylactic acid (D and L isomers) (PDDL) pins welded to PDDL plates by ultrasound vibration and the defect area filled using either a natural bone mineral (NBM) or NBM + autogenous bone (AB) and covered by a native collagen membrane (CM). While the third defect was augmented using NBM+AB+CM, the fourth site was left untreated. At 14weeks, dissected blocks were processed for histomorphometrical analysis [e.g., augmented area (AA)]. ResultsAA values (median in mm(2)) were significantly increased in all guided bone regeneration (GBR) groups [NBM+PDDL+CM (19.74) > NBM+AB+PDDL+CM (16.98) > NBM+AB+CM (16.66)] when compared with the untreated control sites (7.34). Histological analysis has pointed, in the absence of any foreign-body reactions, to biodegradation of both PDDL plates/pins and CM. Conclusions(i) All GBR procedures investigated equally supported bone regeneration, (ii) the application of PDDL+CM may be associated with increased mineralized tissue MT and subsequently AA values than CM alone, and (iii) AB may not improve healing at NBM+PDDL+CM-treated sites.

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