Journal
CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 55, Issue 2, Pages 418-423Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0b013e31825109f6
Keywords
ectopic pregnancy; serum test; biomarkers; proteomics; multiple markers
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Funding
- NICHD NIH HHS [R01 HD036455, K24 HD060687-03, R01 HD036455-10, K24 HD060687, R01-HD036455, K24HD060687] Funding Source: Medline
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Unless an ectopic pregnancy is visible by ultrasound, diagnosis can be a challenge. Differentiating ectopic pregnancies from intrauterine pregnancies can be impossible without intervention or follow-up. This poses a clinical dilemma to the practitioner given the inherent danger to the mother of tubal rupture of an ectopic pregnancy versus the fear of intervening in the case of a desired pregnancy without certainty of diagnosis. Early diagnostic modalities are clearly lacking, and serum biomarkers are currently being investigated as a solution to need for a rapid and accurate test for ectopic pregnancy.
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