Journal
CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 54, Issue 2, Pages 292-304Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0b013e31821ac635
Keywords
carcinosarcoma; uterus; cancer; chemotherapy; radiotherapy
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Carcinosarcoma is a rare but highly aggressive uterine malignancy. Pathologically, carcinosarcoma is a biphasic neoplasm composed of a mixture of malignant epithelial and mesenchymal components. A comprehensive approach for management is recommended with complete surgical staging to assess tumor dissemination followed by multimodal therapy with combinations of external beam irradiation or vaginal brachytherapy and systematic chemotherapy in patients with both early and advanced stage disease.
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