Journal
CLINICAL OBSTETRICS AND GYNECOLOGY
Volume 53, Issue 4, Pages 787-796Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0b013e3181f97a55
Keywords
ovarian tissue transplantation; ovarian tissue cryopreservation; fertility preservation; gonadotoxicity
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Cryopreservation and autotransplantation of ovarian tissue for fertility preservation is considered an experimental technique. However, in some clinical situations it remains the only option. Eleven pregnancies have been reported worldwide from this procedure. Transplantation of ovarian tissue pieces without a vascular pedicle requires the establishment of a new blood supply that takes 5 days. This leads to a substantial loss of follicles in the graft that may limit the longevity of the graft.
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