Journal
CLINICAL NEUROLOGY AND NEUROSURGERY
Volume 115, Issue 8, Pages 1440-1445Publisher
ELSEVIER
DOI: 10.1016/j.clineuro.2013.01.007
Keywords
Lumbar; Discectomy; Facet joint; Facet degeneration; Facet arthrosis; Annulus fibrosis; Disc herniation; Annular closure device
Categories
Funding
- Intrinsic Therapeutics, Inc.
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Lumbar discectomy is an effective treatment for lumbar disc herniation (LDH). Although the majority of patients experience successful outcomes, a significant fraction will experience a recurrence of their back pain due to facet joint degeneration. Facet joint degeneration after discectomy may be the result of excessive nuclear removal, disc space narrowing, and annular injury. This study investigated whether implantation with the Barricaid annular closure device (ACD) during discectomy reduced the rate of facet degeneration. Inclusion criteria were primary lumbar disc herniation failing conservative treatment, Visual Analog Scale (VAS) Leg >= 40/100, Oswestry Disability Index (ODI) >= 40/100 and defects that were <= 60 mm(2) (Barricaid arm only), and patient age 18-75. CT interpretations were collected preoperatively and 12 months post-discectomy. Patients implanted with Barricaid had significantly reduced rates and grades of facet degeneration than patients without Barricaid. Reinforcing the annulus fibrosus with Barricaid during lumbar discectomy may slow the progression of facet joint degeneration. (C) 2013 Elsevier B.V. All rights reserved.
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