Journal
CLINICAL NEPHROLOGY
Volume 80, Issue 1, Pages 67-71Publisher
DUSTRI-VERLAG DR KARL FEISTLE
DOI: 10.5414/CN107333
Keywords
anti-GBM disease; Goodpasture's syndrome; mycophenolate mofetil; glomerulonephritis; pulmonary hemorrhage
Categories
Ask authors/readers for more resources
An 18-year-old woman presented with anemia, pulmonary hemorrhage, and necrotizing glomerulonephritis, and was diagnosed with anti-glomerular basement membrane (anti-GBM) disease. Treatment was undertaken with plasma exchange, mycophenolate mofetil and corticosteroids, due to patient refusal of cyclophosphamide. Clinical remission was successfully induced with this fertility-sparing regimen. A relapse due to therapy non-adherence was successfully treated with a second course of plasmapheresis, mycophenolate, and steroids. Thereafter, 6 months of directly observed therapy resulted in a favorable outcome with well-preserved pulmonary and renal function. This case suggests the possibility that mycophenolate may have a role in the treatment of anti-GBM disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available