4.6 Review

Candida Infections of the Genitourinary Tract

Journal

CLINICAL MICROBIOLOGY REVIEWS
Volume 23, Issue 2, Pages 253-273

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/CMR.00076-09

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Funding

  1. National Institute of Allergy and Infectious Diseases [AI-059681, AI-067665]
  2. National Institutes of Health [AI-51519]

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All humans are colonized with Candida species, mostly Candida albicans, yet some develop diseases due to Candida, among which genitourinary manifestations are extremely common. The forms of genitourinary candidiasis are distinct from each other and affect different populations. While vulvovaginal candidiasis affects mostly healthy women, candiduria occurs typically in elderly, hospitalized, or immunocompromised patients and in neonates. Despite its high incidence and clinical relevance, genitourinary candidiasis is understudied, and therefore, important questions about pathogenesis and treatment guidelines remain to be resolved. In this review, we summarize the current knowledge about genitourinary candidiasis.

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