Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 20, Issue -, Pages 1-55Publisher
ELSEVIER SCI LTD
DOI: 10.1111/1469-0691.12427
Keywords
Acinetobacter; Burkholderia; Enterobacteriaceae; extended-spectrum -lactamase; guideline; infection control; multidrug-resistant Gram-negative; outbreak; Pseudomonas; Stenotrophomonas
Categories
Funding
- Italian Department of Culture, University and Research, Universita Cattolica, Rome, Italy
- German Center for Infectious Research (DZIF)
- Durata
- Waters
- Novartis
- Pfizer
- European Commission
- English Department of Health
- Healthcare Infection Society
- European Centre for Disease Control
- Ecolab
- CareFusion
- Sanofi Pasteur
- Janssen-Cilag
- MSD
- Astellas Pharma
- Becton Dickinson
- Jannssen
- Johnson Johnson
- Spanish Network for Research in Infectious Diseases (REIPI)
- Instituto de Salud Carlos III
- European Development Regional Fund A way to achieve Europe ERDF
- Spanish Network for the Research in Infectious Diseases
- Consejeria de Innovacion
- Junta de Andalucia
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Healthcare-associated infections due to multidrug-resistant Gram-negative bacteria (MDR-GNB) are a leading cause of morbidity and mortality worldwide. These evidence-based guidelines have been produced after a systematic review of published studies on infection prevention and control interventions aimed at reducing the transmission of MDR-GNB. The recommendations are stratified by type of infection prevention and control intervention and species of MDR-GNB and are presented in the form of basic' practices, recommended for all acute care facilities, and additional special approaches' to be considered when there is still clinical and/or epidemiological and/or molecular evidence of ongoing transmission, despite the application of the basic measures. The level of evidence for and strength of each recommendation, were defined according to the GRADE approach.
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