Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 20, Issue 10, Pages O772-O775Publisher
ELSEVIER SCI LTD
DOI: 10.1111/1469-0691.12567
Keywords
Clonal complex398; bone and joint infection; methicillin-susceptible Staphylococcus aureus; molecular epidemiology; nasal carriage; virulence factors
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Funding
- French Ministry of Health
- French Ministry of Education
- Institut National de la Sante et de la Recherche Medicale (INSERM)
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The prevalence of clonal complex (CC)398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.
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