Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 18, Issue -, Pages 12-15Publisher
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2012.03863.x
Keywords
Bacteroides; Bifidobacterium; human milk oligosaccharides; infant gut
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Funding
- National Institutes of Health NIDDK [R01-DK085025, K01-DK077053]
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Clin Microbiol Infect 2012; 18 (Suppl. 4): 1215 Abstract Human milk oligosaccharides (HMO) constitute the third most abundant class of molecules in breast milk. Since infants lack the enzymes required for milk glycan digestion, this group of carbohydrates passes undigested to the lower part of the intestinal tract, where they can be consumed by specific members of the infant gut microbiota. We review proposed mechanisms for the depletion and metabolism of HMO by two major bacterial genera within the infant intestinal microbiota, Bifidobacterium and Bacteroides
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