First detection of VIM-4 metallo-β-lactamase-producing Escherichia coli in Russia

Clin Microbiol Infect 2012; 18: E214E217 Abstract An Escherichia coli isolate co-producing VIM-4 metallo-beta-lactamase and CTX-M-15 extended spectrum beta-lactamase was recovered from the urine of a patient with head trauma in Moscow, Russia. The blaVIM-4 and blaCTX-M-15 genes were carried, respectively, by transmissible plasmids of IncW and IncI1 groups. The nucleotide sequence of the VIM-4-encoding integron was nearly identical to that of In416, which represent a large group of structurally related integrons previously found in Enterobacteriaceae all around the Mediterranean basin. This is the first report of a metallo-beta-lactamase-producing E.similar to coli in Russia.