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Fosfomycin: an oldunew antibiotic

Journal

CLINICAL MICROBIOLOGY AND INFECTION
Volume 18, Issue 1, Pages 4-7

Publisher

ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2011.03636.x

Keywords

Fosfomycin; fosfomycin-trometamol; urinary tract infections

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Fosfomycin is a broad-spectrum antibiotic discovered in Spain in 1969. It has bactericidal activity against a wide range of bacteria, including gram-negative micro-organisms and some gram-positive bacteria, such as staphylococci. Initially fosfomycin was administered parenterally and only to patients with severe infections. Today it is often dispensed as fosfomycintrometamol, an oral formula recommended in the treatment of urinary tract infections. Fosfomycintrometamol in a single dose is indicated for the treatment of women with uncomplicated urinary tract infections.

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