Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 18, Issue 2, Pages E34-E36Publisher
ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2011.03726.x
Keywords
Acinetobacter; carbapenemase; Middle East; multidrug resistant; NDM-2
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Funding
- UAEU [01-10-8-11/09, 1439-08-02-10]
- FMHS [NP/09/16, NP/10/11/1019]
- INSERM U914, France
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Screening 155 carbapenem non-susceptible Acinetobacter baumannii strains recovered in Abu Dhabi hospitals identified two metallo-beta-lactamase blaNDM gene-carrying isolates. They were isolated 4 months apart from the urine of a cancer patient previously treated in Egypt, Lebanon and in the United Arab Emirates. They were clonally related and carried the blaNDM-2 gene recently identified in A.similar to baumannii in Egypt and Israel. Sequences surrounding the blaNDM-2 gene showed significant similarities with those associated with blaNDM-1 in Enterobacteriaceae and A.similar to baumannii. Repeated isolation of blaNDM-2-positive A.similar to baumannii in the Middle East raises the possibility of the local emergence and spread of a unique clone.
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