4.7 Article

Dissemination of New Delhi metallo-ß-lactamase-1-producing Acinetobacter baumannii in Europe

Journal

CLINICAL MICROBIOLOGY AND INFECTION
Volume 18, Issue 9, Pages E362-E365

Publisher

ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2012.03928.x

Keywords

Carbapenemase; Gram-negative rods; New Delhi metallo-ss-lactamase; Tn125

Funding

  1. INSERM [U914]
  2. Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]
  3. Universite Paris XI, France
  4. European Community (TEMPOt-est-QC) [HEALTH-2009-241742]

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Clin Microbiol Infect 2012; 18: E362E365 Abstract Multidrug-resistant and New Delhi metallo-beta-lactamase 1 (NDM-1) -producing Acinetobacter baumannii are increasingly reported. A collection of five NDM-1-positive A. baumannii isolates recovered in four European countries were analysed. Genotyping was performed by pulsed-field gel electrophoresis, multiplex PCR sequence typing, Diversilab and multilocus sequence typing. Three distinct sequence types were identified. All isolates harboured a chromosomally located blaNDM-1 gene within a Tn125-like transposon. One isolate co-expressed another unrelated carbapenemase OXA-23. This report constitutes the first epidemiological study of NDM-1-producing A. baumannii from four countries.

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