4.7 Article

EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)

Journal

CLINICAL MICROBIOLOGY AND INFECTION
Volume 18, Issue 7, Pages E246-E247

Publisher

ELSEVIER SCI LTD
DOI: 10.1111/j.1469-0691.2012.03880.x

Keywords

antifungals; Candida; Cryptococcus; EUCAST; minimum inhibitory concentration; susceptibility testing; yeast

Funding

  1. National Institute of Health (NIHR)
  2. Astellas
  3. Gilead
  4. MSD
  5. Pfizer
  6. Astellas Pharma
  7. bioMerieux
  8. Gilead Sciences
  9. Schering Plough
  10. Soria Melguizo SA
  11. European Union
  12. ALBAN
  13. Spanish Agency for International Cooperation
  14. Spanish Ministry of Culture and Education
  15. Spanish Health Research Fund
  16. Instituto de Salud Carlos III
  17. Ramon Areces Foundation
  18. Mutua Madrilena Foundation
  19. Merck
  20. Vectura
  21. F2G

Ask authors/readers for more resources

Clin Microbiol Infect 2012; 18: E246E247 Abstract The European Committee on Antimicrobial Susceptibility Testing-Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST) has revised the EDef 7.1 document on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for fermentative yeasts. Changes are: dimethylsulphoxide is now the recommended solvent for caspofungin, micafungin and fluconazole; the shelf-life of plates containing the echinocandins prepared from stock solutions in dimethylsulphoxide is extended to 6 months at -80 degrees C; testing of amphotericin and Cryptococcus has been incorporated; and minimum inhibitory concentration ranges for quality control strains and anidulafungin are included.

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