Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 17, Issue 2, Pages 235-237Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1469-0691.2010.03235.x
Keywords
Bedside test; H1N1; influenza A; real-time PCR
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P>To evaluate the clinical reliability of two rapid influenza detection tests (RIDTs), we analyzed 107 specimens from patients with clinically suspected pandemic influenza A/H1N1v by these tests as well as by real-time PCR as a standard. Both RIDTs had a moderate sensitivity (28-32%), a high specificity (93-99%) and a negative predictive value of 80%. These results will impact on the clinical management and isolation precautions in patients with suspected infection. Although a positive RITD is mostly confirmatory, a negative result in the presence of high clinical likelihood of infection should be interpreted with caution and be re-evaluated by PCR.
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