Journal
CLINICAL MICROBIOLOGY AND INFECTION
Volume 16, Issue 6, Pages 630-632Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1469-0691.2009.02944.x
Keywords
blaGES; blaSHV; blaTEM; class 1 integron; extended-spectrum beta-lactamase; Klebsiella pneumoniae; Latin America
Categories
Funding
- Collaborating Center of Sanitary Surveillance (CECOVISA - School of Public Health, University of Sao Paulo)
Ask authors/readers for more resources
A clinical Klebsiella pneumoniae isolate carrying the extended-spectrum beta-lactamase gene variants bla(SHV-40), bla(TEM-116) and bla(GES-7) was recovered. Cefoxitin and ceftazidime activity was most affected by the presence of these genes and an additional resistance to trimethoprim-sulphamethoxazole was observed. The bla(GES-7) gene was found to be inserted into a class 1 integron. These results show the emergence of novel bla(TEM) and bla(SHV) genes in Brazil. Moreover, the presence of class 1 integrons suggests a great potential for dissemination of bla(GES) genes into diverse nosocomial pathogens. Indeed, the bla(GES-7) gene was originally discovered in Enterobacter cloacae in Greece and, to our knowledge, has not been reported elsewhere.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available