Journal
CLINICAL INFECTIOUS DISEASES
Volume 58, Issue 12, Pages 1734-1737Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciu168
Keywords
Imiquimod; chromoblastomycosis; Fonsecaea pedrosoi; innate immunity; antifungal treatment
Categories
Funding
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [2010/52155-0]
- WellcomeTrust
Ask authors/readers for more resources
Chromoblastomycosis is a subcutaneous mycosis that remains a therapeutic challenge, with no standard treatment and high rates of relapse. On the basis of our recent discoveries in mouse models, we tested the efficacy of topical applications of imiquimod to treat patients afflicted with this chronic fungal infection. We report results of treatment for the first 4 recipients of topical imiquimod, all of whom displayed a marked improvement of their lesions, both with and without concurrent oral antifungal therapy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available