Journal
CLINICAL INFECTIOUS DISEASES
Volume 57, Issue -, Pages S32-S38Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/cit300
Keywords
hepatitis C virus; prevention; injection drug users; syringe access; counseling and testing; harm reduction; HCV treatment; HCV vaccine; combination prevention
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Funding
- National Institute on Drug Abuse [R01DA031056, R01DA016017]
- Australian Government Department of Health and Ageing
- National Health and Medical Research Council
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The hepatitis C virus (HCV) virus epidemic is ongoing in the United States and globally. Incidence rates remain high, especially in young adult injection drug users. New outbreaks of HCV in the United States among young adults, in predominantly suburban and rural areas, have emerged and may be fueling an increase in HCV. This paper discusses some key HCV prevention strategies that to date have not been widely researched or implemented, and wherein future HCV prevention efforts may be focused: (1) reducing sharing of drug preparation equipment; (2) HCV screening, and testing and counseling; (3) risk reduction within injecting relationships; (4) injection cessation and breaks; (5) scaled-up needle/syringe distribution, HCV treatment, and vaccines, according to suggestions from mathematical models; and (6) combination prevention. With ongoing and expanding transmission of HCV, there is little doubt that there is a need for implementing what is in the prevention toolbox as well as adding to it. Strong advocacy and resources are needed to overcome challenges to providing the multiple and comprehensive programs that could reduce HCV transmission and associated burden of disease worldwide in people who inject drugs.
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