Journal
CLINICAL INFECTIOUS DISEASES
Volume 57, Issue 4, Pages 564-572Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/cit247
Keywords
mass spectrometry; bacteria; fungi; MALDI-TOF; matrix-assisted laser desorption ionization-time of flight
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Despite widespread application of nucleic acid diagnostics, cultures remain integral in modern laboratories. Because cultures detect a large number of organism types, it is unlikely that they will disappear from clinical practice in the near future. Their downside is slow turn-around time, impacted by time to growth and identification of that growth. The latter is expedited using a new proteomic technology, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
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