Journal
CLINICAL INFECTIOUS DISEASES
Volume 58, Issue 3, Pages 396-399Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/cit715
Keywords
cystic fibrosis; microbiota; Escherichia coli; inflammation; malabsorption
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Funding
- National Institutes of Health [P30 DK089507, K02 HL105543]
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Cystic fibrosis gastrointestinal disease includes nutrient malabsorption and intestinal inflammation. We show that the abundances of Escherichia coli in fecal microbiota were significantly higher in young children with cystic fibrosis than in controls and correlated with fecal measures of nutrient malabsorption and inflammation, suggesting that E. coli could contribute to cystic fibrosis gastrointestinal dysfunction.
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