Journal
CLINICAL INFECTIOUS DISEASES
Volume 54, Issue 6, Pages E51-E54Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/cir904
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Funding
- FIC NIH HHS [D43 TW007124, D43TW007124, D43TW007124-06S1] Funding Source: Medline
- NCATS NIH HHS [UL1 TR000454] Funding Source: Medline
- NCRR NIH HHS [UL1RR025008, UL1 RR025008] Funding Source: Medline
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The pathogenesis of increasing drug resistance among patients with multidrug-resistant or extensively drug-resistant tuberculosis undergoing treatment is poorly understood. Increasing drug resistance found among Mycobacterium tuberculosis recovered from cavitary isolates compared with paired sputum isolates suggests pulmonary cavities may play a role in the development of worsening tuberculosis drug resistance.
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