4.7 Article

Association Between Seasonal Influenza Vaccination in 2008-2009 and Pandemic Influenza A (H1N1) 2009 Infection Among School Students From Kobe, Japan, April-June 2009

Journal

CLINICAL INFECTIOUS DISEASES
Volume 54, Issue 3, Pages 381-383

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/cid/cir787

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Funding

  1. Public Health Center of Kobe
  2. Kobe Institute of Health
  3. Ministry of Health, Labour and Welfare, Japan
  4. Research Foundation for Microbial Diseases of Osaka University, Kanonji Institute

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We assessed the effect of seasonal trivalent inactivated influenza vaccination (TIV) on pandemic influenza 2009 (pH1N1)-related illness from April to June 2009 among 2849 students (aged 12-18 years). TIV was associated with an increase in the frequency of pH1N1-related illness among subjects (adjusted odds ratio, 1.47; 95% confidence interval, 1.14-1.89). TIV during the 2008-2009 season increased the risk of pH1N1-related illness from April to June 2009.

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