Journal
CLINICAL INFECTIOUS DISEASES
Volume 50, Issue 11, Pages 1493-1496Publisher
OXFORD UNIV PRESS INC
DOI: 10.1086/652655
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Funding
- Southeast Regional Center of Excellence for Emerging Infections and Biodefense
- National Institute of Allergy and Infectious Diseases [U54 AI57157]
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Immunosuppressed patients receiving oseltamivir for 2009 novel H1N1 influenza A infection may develop drug resistance, leading to treatment failure. Intravenous zanamivir was administered on a compassionate-use basis to a profoundly immunosuppressed pediatric patient with severe oseltamivir-resistant novel H1N1 pneumonia. The regimen was well tolerated and was associated with a decrease in viral burden.
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